Myocardial iron assessment by T2* cardiovascular magnetic resonance at 3 Tesla

نویسندگان

  • Mohammed H Alam
  • Gillian C Smith
  • Taigang He
  • John Paul Carpenter
  • Arun J Baksi
  • Ricardo Wage
  • Peter Drivas
  • Karen Symmonds
  • David Firmin
  • Dudley J Pennell
چکیده

Background Chronic iron overload is prevalent and prognosis relates to the severity of cardiac siderosis. The black blood (BB) T2* technique is validated, with calibration against myocardial tissue iron at 1.5T. There are potential advantages of 3T over 1.5T in assessing T2*, but preliminary studies at 3T used white blood imaging, had small patient numbers, methodological differences, and poor signal-noise ratio in severe iron overload precluding assessment across a wide dynamic range. A novel noise correction (NC) algorithm is superior to other techniques in severe iron loading. We assessed BB T2* iron measurement at 3T against the 1.5T gold standard and incorporated the NC algorithm.

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عنوان ژورنال:

دوره 16  شماره 

صفحات  -

تاریخ انتشار 2014